Dissecting the complex interplay between AD and cerebrovascular dysfunction in human brains across the genetic and molecular layers through functional genomics
Our work provides novel insights into the links between cerebrovascular dysfunction and AD and identifies genes and regulatory elements mediating AD genetic risk through CVCs.
Authors
- Celeste M M. Karch (ORCID: https://orcid.org/0000-0002-6854-5547)
- Oscar Harari (ORCID: https://orcid.org/0000-0002-2635-6975)
- Taylor Bertucci (ORCID: https://orcid.org/0009-0008-1017-6807)
- Greg Sutherland
- Bruno A. Benítez (ORCID: https://orcid.org/0000-0002-2699-3878)
- Çağhan Kızıl (ORCID: https://orcid.org/0000-0002-8164-9762)
- Ricardo B. D. d'Oliveira
- Sally Temple (ORCID: https://orcid.org/0000-0001-7301-783X)
- Elanur Yilmaz
- Ekaterina Aladyeva
Institutions
- The University of Sydney (AU)
- Beth Israel Deaconess Medical Center (US)
- Washington University in St. Louis (US)
- Columbia University Irving Medical Center (US)
- The Ohio State University Wexner Medical Center (US)
- Neural Stem Cell Institute (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70855_101122
- Primary Topic
- Single-cell and spatial transcriptomics
- Type
- article
- Field-Weighted Citation Impact
- 0.00