Body mass index and chemotherapy completion among patients with newly diagnosed ovarian cancer

Among patients with ovarian cancer treated since 2012, the overall RDI was low. Relative dose intensity was higher among patients with a BMI of 25 or higher compared with a BMI below 25. Most dose modifications occurred during treatment and not before initiation. Studies with body composition data and interventions that maximize chemotherapy completion during treatment are warranted.

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Publication Details

Journal
JNCI Cancer Spectrum
Published
2025-12-23
DOI
https://doi.org/10.1093/jncics/pkaf121
Primary Topic
Cancer Risks and Factors
Type
article
Field-Weighted Citation Impact
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article

Body mass index and chemotherapy completion among patients with newly diagnosed ovarian cancer

Denise Esserman, Elena Ratner, Leah M. Ferrucci, Melinda L. Irwin et al.
JNCI Cancer Spectrum
Cancer Risks and Factors
article

Body mass index and chemotherapy completion among patients with newly diagnosed ovarian cancer

Denise Esserman, Elena Ratner, Leah M. Ferrucci, Melinda L. Irwin, Brenda Cartmel, Tracy E. Crane, Amanika Kumar, Fang Yong Li, Matthew P Schlumbrecht, Anlan Cao
article en

Abstract

Among patients with ovarian cancer treated since 2012, the overall RDI was low. Relative dose intensity was higher among patients with a BMI of 25 or higher compared with a BMI below 25. Most dose modifications occurred during treatment and not before initiation. Studies with body composition data and interventions that maximize chemotherapy completion during treatment are warranted.

JNCI Cancer SpectrumVol. 10(1)
Mayo Clinic (US), University of Miami (US), Yale Cancer Center (US), Yale University (US), Mayo Clinic in Arizona (US), Mayo Clinic in Florida (US), Sylvester Comprehensive Cancer Center (US)
Good health and well-being
Openalex Percentile: Top 31%
Cancer Risks and Factors
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Body mass index and chemotherapy completion among patients with newly diagnosed ovarian cancer — Denise Esserman, Elena Ratner, et al. · JNCI Cancer Spectrum (2025) | TGRS Research Map | TGRS