Meeting report for the 2025 UC Irvine Center for Neural Circuit Mapping conference: The Changing Brain

The 5th annual conference of the UC Irvine Center for Neural Circuit Mapping (CNCM), "The Changing Brain," was held August 18-20, 2025, at the Irvine Marriott in Irvine, California, followed by additional conference-associated workshops on spatial transcriptomics and viral-genetic tools on August 21 at UCI. With over 380 participants from academia and industry, the meeting highlighted recent advances in neural circuit mapping across evolution, development, function, and disease. The meeting featured strong trainee engagement through travel awards and poster sessions. The UCI CNCM annual meeting series continues to grow as a leading forum for advancing neural circuit research relevant to normal brain function and psychiatric and neurological disorders.