Prediabetic amylin hypersecretion impairs brain glucose regulation
Prediabetic amylin hypersecretion increases brain amylin level and exacerbates amylin receptor signaling controlling glycolysis, leading to impairments of glycolytic flux and memory.
Authors
- H. Liu
- Florin Despa (ORCID: https://orcid.org/0000-0002-5879-6449)
- Ravichandra Shivalingappa Davargaon (ORCID: https://orcid.org/0000-0001-5526-8037)
- Pradeep Kachroo (ORCID: https://orcid.org/0000-0003-4176-5096)
- Deepak Kotiya (ORCID: https://orcid.org/0000-0001-5794-8626)
- Noah Leibold (ORCID: https://orcid.org/0000-0001-7737-0382)
- Nirmal Verma (ORCID: https://orcid.org/0000-0002-9218-2475)
Institutions
- University of Kentucky (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70855_105720
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00