Intraventicular Delivery of IL‐27 Gene Exerts Neuroprotection and Ameliorates Cognitive Deficits in A Mouse Model for Alzheimer's Disease

Together with our previous reported findings, data from the current study suggest an intrinsic, neuroprotective pathway of IL-27 that alleviates neuronal damage associated with AD via modulation of the inflammatory responses within the CNS.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70855_100804
Primary Topic
Psoriasis: Treatment and Pathogenesis
Type
article
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0.00
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article

Intraventicular Delivery of IL‐27 Gene Exerts Neuroprotection and Ameliorates Cognitive Deficits in A Mouse Model for Alzheimer's Disease

Zichun Xiao
Alzheimer s & Dementia
Psoriasis: Treatment and Pathogenesis
article

Intraventicular Delivery of IL‐27 Gene Exerts Neuroprotection and Ameliorates Cognitive Deficits in A Mouse Model for Alzheimer's Disease

Zichun Xiao
article en

Abstract

Together with our previous reported findings, data from the current study suggest an intrinsic, neuroprotective pathway of IL-27 that alleviates neuronal damage associated with AD via modulation of the inflammatory responses within the CNS.

Alzheimer s & DementiaVol. 21(S1)
Tianjin Medical University General Hospital (CN)
Partnerships for the goals
Openalex Percentile: Top 36%
Psoriasis: Treatment and Pathogenesis
DOIOpen Access PDFOpenAlex
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