Glymphatic alterations are linked to white matter topological network dysfunction in Alzheimer's Disease
ALPS is associated with alterations in the structural topological network in AD. Mediators such as Aβ, Tau, neurodegeneration, inflammation, and synaptic dysfunction play significant roles in the association. The Aβ to Tau and Aβ to neurodegeneration pathways also mediate the association.
Authors
- Liyong Wu
- Pedro Rosa‐Neto
- Min Chu
Institutions
- Montreal Neurological Institute and Hospital (CA)
- Capital Medical University (CN)
- McGill University Health Centre (CA)
- McGill University (CA)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_102806
- Primary Topic
- Cerebrospinal fluid and hydrocephalus
- Type
- article
- Field-Weighted Citation Impact
- 0.00