Rare Variant Association Analysis Reveals <i>B3GNT9, RANBP10, and C1QL4</i> As Potential Genes for Cognitive Preservation in the Mid‐Western Amish

Our gene-based genome-wide RV association analyses identified suggestive associations with cognitive preservation in the Amish. These results underscore the potential significance of RVs in elucidating the full genetic architecture of AD.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70855_102970
Primary Topic
Genetic Mapping and Diversity in Plants and Animals
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article
Field-Weighted Citation Impact
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article

Rare Variant Association Analysis Reveals B3GNT9, RANBP10, and C1QL4 As Potential Genes for Cognitive Preservation in the Mid‐Western Amish

Daniel A. Dorfsman, Kristy Miskimen, Patrice Whitehead, Michael Cuccaro et al.
Alzheimer s & Dementia
Genetic Mapping and Diversity in Plants and Animals
article

Rare Variant Association Analysis Reveals B3GNT9, RANBP10, and C1QL4 As Potential Genes for Cognitive Preservation in the Mid‐Western Amish

Daniel A. Dorfsman, Kristy Miskimen, Patrice Whitehead, Michael Cuccaro, Leighanne R. Main, Jason E. Clouse, Sharlene D. Herington, Yining Liu, Sherri D. Hochstetler, Jeffery M. M Vance, Michael B. Prough, Reneé A. Laux, Laura J. Caywood, Yeunjoo E. Song, Weihuan Wang, William K. Scott, Sarada L. Fuzzell, Alan J. Lerner, Dawn M. Miller, Audrey Lynn, Alex V. Gulyayev, Andrew F Zaman, Margaret Pericak‐Vance, Ping Wang, Noel C. Moore, Jonathan L Haines, Paula K. Ogrocki, Larry D Adams
article en

Abstract

Our gene-based genome-wide RV association analyses identified suggestive associations with cognitive preservation in the Amish. These results underscore the potential significance of RVs in elucidating the full genetic architecture of AD.

Alzheimer s & DementiaVol. 21(S1)
University of Miami (US), University Hospitals of Cleveland (US), Dr. John T. Macdonald Foundation (US), University School (US), Case Western Reserve University (US)
Openalex Percentile: Top 25%
Genetic Mapping and Diversity in Plants and Animals
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Rare Variant Association Analysis Reveals <i>B3GNT9, RANBP10, and C1QL4</i> As Potential Genes for Cognitive Preservation in the Mid‐Western Amish — Daniel A. Dorfsman, Kristy Miskimen, et al. · Alzheimer s & Dementia (2025) | TGRS Research Map | TGRS