Biomolecular Insights Into the Antifungal Activity of <i>Allium</i> Species Constituents: From Mechanisms to Applications

Saponins from <i>Allium</i> species represent promising adjuncts for overcoming antifungal drug resistance and may expand treatment options beyond traditional sulfur-derived compounds. These bioactive molecules also show potential for agricultural use against soil-borne pathogens like <i>F. oxysporum</i>, as well as food preservation applications against spoilage fungi such as <i>Penicillium italicum</i> and <i>A. niger</i>. Overall, <i>Allium</i> species constitute a valuable natural source of antifungal agents with broad pharmaceutical and agricultural relevance.

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Publication Details

Journal
Iranian journal of pharmaceutical research
Published
2025-12-13
DOI
https://doi.org/10.5812/ijpr-162031
Primary Topic
Garlic and Onion Studies
Type
article
Field-Weighted Citation Impact
0.00

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article

Biomolecular Insights Into the Antifungal Activity of Allium Species Constituents: From Mechanisms to Applications

Behzad Zolfaghari, Masoud Sadeghi, Mustafa Ghanadian, Saeid Eslami
Iranian journal of pharmaceutical research
Garlic and Onion Studies
article

Biomolecular Insights Into the Antifungal Activity of Allium Species Constituents: From Mechanisms to Applications

Behzad Zolfaghari, Masoud Sadeghi, Mustafa Ghanadian, Saeid Eslami
article en

Abstract

Saponins from <i>Allium</i> species represent promising adjuncts for overcoming antifungal drug resistance and may expand treatment options beyond traditional sulfur-derived compounds. These bioactive molecules also show potential for agricultural use against soil-borne pathogens like <i>F. oxysporum</i>, as well as food preservation applications against spoilage fungi such as <i>Penicillium italicum</i> and <i>A. niger</i>. Overall, <i>Allium</i> species constitute a valuable natural source of antifungal agents with broad pharmaceutical and agricultural relevance.

Iranian journal of pharmaceutical researchVol. 24(1)
Isfahan University of Medical Sciences (IR)
Isfahan University of Medical Sciences
Zero hunger
Openalex Percentile: Top 25%
Garlic and Onion Studies
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