Real-world efficacy and safety of selpercatinib in <i>RET</i> -mutant medullary thyroid cancer at a Tertiary Referral Center

In real-word settings, selpercatinib showed high efficacy and tolerability, particularly as first-line treatment. Our findings support its use as the preferred initial targeted treatment for RET-driven MTC beyond clinical trial populations.

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Publication Details

Journal
European Journal of Endocrinology
Published
2025-11-26
DOI
https://doi.org/10.1093/ejendo/lvaf256
Citations
1
Primary Topic
Thyroid Cancer Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
1.29
Controls
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article

Real-world efficacy and safety of selpercatinib in RET -mutant medullary thyroid cancer at a Tertiary Referral Center

Yara Maria Machlah, Tim Brandenburg, F. Weber, Lahner Harald et al.
1 citations
European Journal of Endocrinology
Thyroid Cancer Diagnosis and Treatment
1.29
article

Real-world efficacy and safety of selpercatinib in RET -mutant medullary thyroid cancer at a Tertiary Referral Center

Yara Maria Machlah, Tim Brandenburg, F. Weber, Lahner Harald, Dagmar Führer, Sarah Theurer, Lynn Marlene Srasra
article en
1 citations

Abstract

In real-word settings, selpercatinib showed high efficacy and tolerability, particularly as first-line treatment. Our findings support its use as the preferred initial targeted treatment for RET-driven MTC beyond clinical trial populations.

European Journal of EndocrinologyVol. 193(6)
European Neuroendocrine Tumor Society (DE), West Cancer Center (US), Essen University Hospital (DE), University of Duisburg-Essen (DE)
Good health and well-being
Openalex Percentile: Top 13%
Thyroid Cancer Diagnosis and Treatment
1.29
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