Impact of Atherosclerosis Comorbidity on Cortical Microstructure in Alzheimer's Disease Using Diffusion MRI: Evidence from an Autopsy‐Confirmed Cohort

These findings highlight the potential of cortical diffusivity in detecting distinct patterns of microstructural changes in individuals with the same ADNC severity but varying levels of ACW severity. This underscores the utility of cortical diffusivity for patient stratification in clinical practice and trials.

Authors

Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70856_097257
Primary Topic
Advanced Neuroimaging Techniques and Applications
Type
article
Field-Weighted Citation Impact
0.00
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article

Impact of Atherosclerosis Comorbidity on Cortical Microstructure in Alzheimer's Disease Using Diffusion MRI: Evidence from an Autopsy‐Confirmed Cohort

Pegah Khosropanah, Steven A. Chance, Mario Torso, Gerard R Ridgway et al.
Alzheimer s & Dementia
Advanced Neuroimaging Techniques and Applications
article

Impact of Atherosclerosis Comorbidity on Cortical Microstructure in Alzheimer's Disease Using Diffusion MRI: Evidence from an Autopsy‐Confirmed Cohort

Pegah Khosropanah, Steven A. Chance, Mario Torso, Gerard R Ridgway, Ian Hardingham
article en

Abstract

These findings highlight the potential of cortical diffusivity in detecting distinct patterns of microstructural changes in individuals with the same ADNC severity but varying levels of ACW severity. This underscores the utility of cortical diffusivity for patient stratification in clinical practice and trials.

Alzheimer s & DementiaVol. 21(S2)
Openalex Percentile: Top 31%
Advanced Neuroimaging Techniques and Applications
DOIOpen Access PDFOpenAlex
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Impact of Atherosclerosis Comorbidity on Cortical Microstructure in Alzheimer's Disease Using Diffusion MRI: Evidence from an Autopsy‐Confirmed Cohort — Pegah Khosropanah, Steven A. Chance, et al. · Alzheimer s & Dementia (2025) | TGRS Research Map | TGRS