PEDOSA-7: Development, Validation, and Clinical Utility of a Simplified Screening Tool for Pediatric Obstructive Sleep Apnea—A Pilot Study

Introduction: Pediatric obstructive sleep apnea (OSA) remains underdiagnosed due to reliance on complex screening tools. This pilot study developed and validated the PEDOSA-7, a 7-item binary-response (Yes/No) questionnaire, to streamline OSA screening. Materials and Methods: A cross-sectional analysis of 83 children (aged from 3 to 16 years) with sleep complaints compared PEDOSA-7 performance with polysomnography (apnea–hypopnea index (AHI) ≥5 for OSA) and the Pediatric Sleep Questionnaire (PSQ). Results: Of the cohort, 31.3% (26/83) had OSA (AHI ≥5). The OSA group exhibited a higher mean body mass index (BMI; 22.3 vs. 18.0; P < 0.05) and a strong BMI–AHI correlation ( r = 0.73). PEDOSA-7 demonstrated sensitivity of 84.6%, specificity of 54.4%, negative predictive value (NPV) of 88.6%, and area under the curve of 0.728 at a cutoff score ≥3. Key items (snoring and breathing pauses) showed high sensitivity (92%). Internal consistency was suboptimal (Cronbach α = 0.49), reflecting item redundancy. Compared with PSQ, PEDOSA-7 achieved better sensitivity (PSQ: 61.3%) with superior practicality due to its binary scoring. Lowering the AHI threshold to >1 improved specificity (83.3%) but reduced sensitivity (37.1%), highlighting trade-offs in screening accuracy. Discussion: PEDOSA-7 offers a rapid, clinician-friendly tool for OSA risk stratification, particularly in resource-limited settings, with a high NPV minimizing unnecessary referrals. Limitations include a small, gender-imbalanced sample (non-OSA group: all males) and a lack of cultural/age diversity. Future studies should validate the tool in larger cohorts and refine its psychometric properties. Conclusion: The PEDOSA-7 balances diagnostic accuracy and usability, serving as an alternative screening tool to improve OSA detection. Furthermore, validation in diverse populations is warranted.

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Publication Details

Journal
Journal of Pediatric Pulmonology
Published
2025-09-01
DOI
https://doi.org/10.4103/jopp.jopp_14_25
Primary Topic
Obstructive Sleep Apnea Research
Type
article
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article

PEDOSA-7: Development, Validation, and Clinical Utility of a Simplified Screening Tool for Pediatric Obstructive Sleep Apnea—A Pilot Study

Gautam Ghosh, Somnath Maity, Pallab Chatterjee, Arup Haldar et al.
Journal of Pediatric Pulmonology
Obstructive Sleep Apnea Research
article

PEDOSA-7: Development, Validation, and Clinical Utility of a Simplified Screening Tool for Pediatric Obstructive Sleep Apnea—A Pilot Study

Gautam Ghosh, Somnath Maity, Pallab Chatterjee, Arup Haldar, Arpita Halder Chatterjee, Subhasis Roy, Dipankar Datta
article en

Abstract

Introduction: Pediatric obstructive sleep apnea (OSA) remains underdiagnosed due to reliance on complex screening tools. This pilot study developed and validated the PEDOSA-7, a 7-item binary-response (Yes/No) questionnaire, to streamline OSA screening. Materials and Methods: A cross-sectional analysis of 83 children (aged from 3 to 16 years) with sleep complaints compared PEDOSA-7 performance with polysomnography (apnea–hypopnea index (AHI) ≥5 for OSA) and the Pediatric Sleep Questionnaire (PSQ). Results: Of the cohort, 31.3% (26/83) had OSA (AHI ≥5). The OSA group exhibited a higher mean body mass index (BMI; 22.3 vs. 18.0; P < 0.05) and a strong BMI–AHI correlation ( r = 0.73). PEDOSA-7 demonstrated sensitivity of 84.6%, specificity of 54.4%, negative predictive value (NPV) of 88.6%, and area under the curve of 0.728 at a cutoff score ≥3. Key items (snoring and breathing pauses) showed high sensitivity (92%). Internal consistency was suboptimal (Cronbach α = 0.49), reflecting item redundancy. Compared with PSQ, PEDOSA-7 achieved better sensitivity (PSQ: 61.3%) with superior practicality due to its binary scoring. Lowering the AHI threshold to >1 improved specificity (83.3%) but reduced sensitivity (37.1%), highlighting trade-offs in screening accuracy. Discussion: PEDOSA-7 offers a rapid, clinician-friendly tool for OSA risk stratification, particularly in resource-limited settings, with a high NPV minimizing unnecessary referrals. Limitations include a small, gender-imbalanced sample (non-OSA group: all males) and a lack of cultural/age diversity. Future studies should validate the tool in larger cohorts and refine its psychometric properties. Conclusion: The PEDOSA-7 balances diagnostic accuracy and usability, serving as an alternative screening tool to improve OSA detection. Furthermore, validation in diverse populations is warranted.

Journal of Pediatric PulmonologyVol. 4(3)
Government Medical College (IN), Rabindranath Tagore International Institute of Cardiac Sciences (IN), Institute of Post Graduate Medical Education and Research (IN), Institute of Neurosciences Kolkata (IN), Manipal Hospital (IN), Medical College and Hospital, Kolkata (IN)
Openalex Percentile: Top 34%
Obstructive Sleep Apnea Research
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