The Inflammatory Signature of RHI in Athletes at Risk of CTE

Our results provide evidence that distinct inflammatory profiles exist between former contact sports athletes with RHI, patients with AD and HC. As well, we show a relationship between markers of inflammation and neurodegeneration. Identifying specific inflammatory markers relevant to RHI could support the development of targeted therapies to halt neurodegeneration in RHI. 1. Neurology 93(5), e497(2019); 2. Front Neurol 4, 18(2013); 3. Concussion 2(1), CNC30(2017).

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70856_096745
Primary Topic
Traumatic Brain Injury Research
Type
article
Field-Weighted Citation Impact
0.00
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article

The Inflammatory Signature of RHI in Athletes at Risk of CTE

C. H. Tator, Chloe Anastassiadis, Lian L. Troncoso, Carmela M. Tartaglia et al.
Alzheimer s & Dementia
Traumatic Brain Injury Research
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The Inflammatory Signature of RHI in Athletes at Risk of CTE

C. H. Tator, Chloe Anastassiadis, Lian L. Troncoso, Carmela M. Tartaglia, Mozhgan Khodadadi, Simrika Thapa
article en

Abstract

Our results provide evidence that distinct inflammatory profiles exist between former contact sports athletes with RHI, patients with AD and HC. As well, we show a relationship between markers of inflammation and neurodegeneration. Identifying specific inflammatory markers relevant to RHI could support the development of targeted therapies to halt neurodegeneration in RHI. 1. Neurology 93(5), e497(2019); 2. Front Neurol 4, 18(2013); 3. Concussion 2(1), CNC30(2017).

Alzheimer s & DementiaVol. 21(S2)
University Health Network (CA), University of Toronto (CA), Toronto Western Hospital (CA), Occupational Cancer Research Centre (CA), Ontario Brain Institute (CA)
Good health and well-being
Openalex Percentile: Top 30%
Traumatic Brain Injury Research
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