The effect of hearing loss on a rat model with genetic susceptibility to Alzheimer's disease
Ultimately, our preclinical data help provide novel insight into the interplay between hearing loss and genetic susceptibility to AD. Collectively, our results demonstrate that while AD-related impairments were evident in our prodromal model of AD, the degree of noise-induced hearing loss used in the present study was insufficient to exacerbate these impairments.
Authors
- Shawn N. Whitehead (ORCID: https://orcid.org/0000-0003-4728-8067)
- Sarah J. Myers (ORCID: https://orcid.org/0000-0003-0939-4571)
- Ashley L. Schormans (ORCID: https://orcid.org/0000-0003-3327-6591)
- Brian L. Allman (ORCID: https://orcid.org/0000-0001-8793-2019)
- Salonee V. Patel (ORCID: https://orcid.org/0000-0003-0148-728X)
- Parinita Arora
- Sophia MH Robinson
- Sarah H Hayes
Institutions
- Western University (CA)
- University of Rochester (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70855_104043
- Primary Topic
- Hearing, Cochlea, Tinnitus, Genetics
- Type
- article
- Field-Weighted Citation Impact
- 0.00