Integration Analysis of Metabolome and Transcriptome Reveals the Effect of Lipopolysaccharide on Ovary Response to Stimulation
This study provided evidence that inflammation has damaging effect on ovary response to controlled ovarian stimulation, linked to dysfunctions in lipid, carbohydrate, and amino acid metabolism. IL-17 signal pathways may play a critical role in this process.
Authors
- Yudan Zhang (ORCID: https://orcid.org/0000-0003-3311-789X)
- Xin Mu
- Mei‐Li Pei
- Feng Zhu
Institutions
- Northwest Women's and Children's Hospital (CN)
- First Affiliated Hospital of Xi'an Jiaotong University (CN)
Publication Details
- Journal
- Immunity Inflammation and Disease
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/iid3.70309
- Primary Topic
- Reproductive Biology and Fertility
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Yakult Bio-Science Foundation
- Key Research and Development Projects of Shaanxi Province