Stroke‐Induced Gut Dysbiosis Increases Alzheimer's Disease Risk: Insights from Immunohistochemistry and Single‐Cell Spatial Transcriptomics
Stroke donor FMT-induced gut dysbiosis exacerbates AD pathology, emphasizing the critical role of the gut-brain axis in linking stroke and AD. Targeting gut dysbiosis may offer a novel therapeutic strategy for stroke-related AD progression.
Authors
- Amitai Zuckerman
- Ai‐Ling Lin
- Meera Govindarajan
- Aaron C. Ericsson (ORCID: https://orcid.org/0000-0002-3053-7269)
- Chetan Aware
- Zezong Gu (ORCID: https://orcid.org/0000-0002-2411-7460)
- Kira L. Ivanich
- Jiankun Cui
- Lixin Ma
Institutions
- University of Missouri (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70855_106078
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.00