Impacts of chronic jetlag on compensatory angiogenesis in 5XFAD mice

When exposed to circadian disruption across the highest period of amyloid beta deposition, 5xFAD animals display increased measures of rhythmicity that we propose may be due to a higher response to light. This will be tested in further experiments. This indicates that repeated phase shift exposure during the period of amyloid beta deposition may improve measures of locomotor activity. We will present data on the implications on vascular health and recovery.