Association between brain tissue volume loss and blood inflammatory biomarkers in cognitively impaired participants with old age

The association between brain tissue volume loss and levels of IL1β and T-tau suggests that IL1β and T-tau in the blood are potential biomarkers for cognitive impairment in elderly people. Thus, they could be used for future assessment of disease severity and response to treatment after diagnosis in elderly people who might progress to cognitive impairment.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70856_100769
Primary Topic
Neuroinflammation and Neurodegeneration Mechanisms
Type
article
Field-Weighted Citation Impact
0.00
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article

Association between brain tissue volume loss and blood inflammatory biomarkers in cognitively impaired participants with old age

Yunan Tian, Geon‐Ho Jahng, Hak Young Rhee
Alzheimer s & Dementia
Neuroinflammation and Neurodegeneration Mechanisms
article

Association between brain tissue volume loss and blood inflammatory biomarkers in cognitively impaired participants with old age

Yunan Tian, Geon‐Ho Jahng, Hak Young Rhee
article en

Abstract

The association between brain tissue volume loss and levels of IL1β and T-tau suggests that IL1β and T-tau in the blood are potential biomarkers for cognitive impairment in elderly people. Thus, they could be used for future assessment of disease severity and response to treatment after diagnosis in elderly people who might progress to cognitive impairment.

Alzheimer s & DementiaVol. 21(S2)
Kyung Hee University (KR), Kyung Hee University Hospital at Gangdong (KR)
Good health and well-being
Openalex Percentile: Top 39%
Neuroinflammation and Neurodegeneration Mechanisms
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