Modulating IL‐1R1/IL‐1RAP Signaling: A Dual Approach to Reducing Neuroinflammation and Tau Pathology

Our results indicate that inhibiting the IL-1R1/IL-1RAP signaling axis is a promising approach to reducing neuroinflammation and tau pathology. This approach could also be effective for treating other inflammatory diseases.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70855_105590
Primary Topic
IL-33, ST2, and ILC Pathways
Type
article
Field-Weighted Citation Impact
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article

Modulating IL‐1R1/IL‐1RAP Signaling: A Dual Approach to Reducing Neuroinflammation and Tau Pathology

Kiran Bhaskar, Somayeh Dadras, Cristian Bologa, Tione Buranda
Alzheimer s & Dementia
IL-33, ST2, and ILC Pathways
article

Modulating IL‐1R1/IL‐1RAP Signaling: A Dual Approach to Reducing Neuroinflammation and Tau Pathology

Kiran Bhaskar, Somayeh Dadras, Cristian Bologa, Tione Buranda
article en

Abstract

Our results indicate that inhibiting the IL-1R1/IL-1RAP signaling axis is a promising approach to reducing neuroinflammation and tau pathology. This approach could also be effective for treating other inflammatory diseases.

Alzheimer s & DementiaVol. 21(S1)
University of New Mexico (US)
Good health and well-being
Openalex Percentile: Top 36%
IL-33, ST2, and ILC Pathways
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Modulating IL‐1R1/IL‐1RAP Signaling: A Dual Approach to Reducing Neuroinflammation and Tau Pathology — Kiran Bhaskar, Somayeh Dadras, et al. · Alzheimer s & Dementia (2025) | TGRS Research Map | TGRS