Healthcare-Associated Infections: Knowledge Score and Awareness Among Nurses in Hospitals from North-East Romania

<i>Background and Objectives</i>: Healthcare-associated infections (HAIs) are a major cause of morbidity and mortality and can lead to serious long-term consequences, increased hospital length stay, higher rates of antibiotic resistance, and additional financial costs. The study aim was to highlight important aspects related to the level of knowledge of HAIs, risk factors for HAI and methods of preventing HAIs among nurses from urban hospitals in the North-East of Romania. <i>Materials and Methods</i>: We conducted a cross-sectional study on the level of knowledge of HAI problems among medical personnel (nurses). The study group consisted of 288 nurses who responded online to a questionnaire. <i>Results</i>: Multivariate analysis suggested that 45.5% of the value of the knowledge score of prevention and limitation of HAIs could be determined by the answers to the questions regarding the importance of the nurse role, professional experience, and training. Moreover 84.6% of the knowledge score could be determined by the answers to the questions regarding the assessment of the importance of factors related to lack of medical personnel, professional burnout, insufficient knowledge and staff training, inefficient team, poor collaboration within departments, stressful work environment, staff health status, multiple tasks at work (<i>p</i> = 0.038). While 50% of the knowledge score could be explained by responses regarding personal problems related to daily activity; physical and mental health status; and physical, psychological, and social components (<i>p</i> = 0.038). <i>Conclusions</i>: Our study highlighted aspects of the level of knowledge regarding HAIs among nurses, an issue that plays a key role in hospital management. Overall, the knowledge score for the prevention and limitation of HAIs was higher in nurses/females aged over 40 and in nurses with more than 15 years of experience.