Unraveling High‐Risk Cell‐Cell Interactions in Alzheimer's Disease Using an Integrative Single Cell Analysis
This study highlights the novelty of our pipeline in integrating RNA-seq data to identify robust intercellular communication networks in AD. By prioritizing consistent interactions across datasets, we provide insights into AD pathology that inform experimental validation and therapeutic development.
Authors
- Travis S. Johnson (ORCID: https://orcid.org/0000-0002-4628-2256)
- Jie Zhang
- Jiahui Liu
- Kun Huang
Institutions
- Indiana Biosciences Research Institute (US)
- Indiana University – Purdue University Indianapolis (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70855_105077
- Primary Topic
- Single-cell and spatial transcriptomics
- Type
- article
- Field-Weighted Citation Impact
- 0.00