Association of Serum IL-17A and IL-23 Levels With Alopecia Areata: A Cross-Sectional Comparative Study

Elevated IL-17A levels are associated with AA severity and differ across clinical subtypes, suggesting a role in disease progression and phenotype variation. IL-23 is consistently elevated in AA, highlighting its potential as a biomarker for disease activity. These findings provide insight into cytokine dysregulation in AA and may inform future therapeutic strategies.

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Publication Details

Journal
Cureus
Published
2025-12-24
DOI
https://doi.org/10.7759/cureus.100011
Primary Topic
Hair Growth and Disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Association of Serum IL-17A and IL-23 Levels With Alopecia Areata: A Cross-Sectional Comparative Study

Wasi Deen Ahmed, Mohammad Abul Kalam Azad, Pranam Swapan Dash, Mohammad Jamal Uddin et al.
Cureus
Hair Growth and Disorders
article

Association of Serum IL-17A and IL-23 Levels With Alopecia Areata: A Cross-Sectional Comparative Study

Wasi Deen Ahmed, Mohammad Abul Kalam Azad, Pranam Swapan Dash, Mohammad Jamal Uddin, A.T.M. Asaduzzaman, Md. Shihab Talukder
article en

Abstract

Elevated IL-17A levels are associated with AA severity and differ across clinical subtypes, suggesting a role in disease progression and phenotype variation. IL-23 is consistently elevated in AA, highlighting its potential as a biomarker for disease activity. These findings provide insight into cytokine dysregulation in AA and may inform future therapeutic strategies.

CureusVol. 17(12)
University of Dhaka (BD), Directorate General of Health Services (BD)
Good health and well-being
Openalex Percentile: Top 28%
Hair Growth and Disorders
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