Longitudinal Surface‐Based Morphometry Changes in the Hippocampus in Dementia

Hippocampal volume reductions are well-established markers of AD, but surface-based features like curvature, gyrification, and thickness provide additional insights, revealing changes that volume alone may miss. These findings highlight the importance of integrating surface-based metrics with volumetric analyses to improve understanding of disease mechanisms and interventions.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70856_101579
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Longitudinal Surface‐Based Morphometry Changes in the Hippocampus in Dementia

Romeo Penheiro, Cassandra Morrison, Peter Zhukovsky, John AE Anderson et al.
Alzheimer s & Dementia
Dementia and Cognitive Impairment Research
article

Longitudinal Surface‐Based Morphometry Changes in the Hippocampus in Dementia

Romeo Penheiro, Cassandra Morrison, Peter Zhukovsky, John AE Anderson, Salah Aziz
article en

Abstract

Hippocampal volume reductions are well-established markers of AD, but surface-based features like curvature, gyrification, and thickness provide additional insights, revealing changes that volume alone may miss. These findings highlight the importance of integrating surface-based metrics with volumetric analyses to improve understanding of disease mechanisms and interventions.

Alzheimer s & DementiaVol. 21(S2)
Centre for Addiction and Mental Health (CA), University of Houston (US), Carleton University (CA)
Openalex Percentile: Top 35%
Dementia and Cognitive Impairment Research
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