Na[18F]F PET/CT quantification in spondyloarthritis: comparative evaluation of SUV normalization approaches

Na[<sup>18</sup>F]F uptake quantification of lesions in the axial skeleton of SpA patients can be performed cross-sectionally and longitudinally with simplified uptake measures, particularly SUV<sub>peak</sub>, normalized using LBM or SV. This offers a more reliable approach to evaluating disease activity and treatment responses compared to BW.

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Publication Details

Journal
EJNMMI Research
Published
2025-12-24
DOI
https://doi.org/10.1186/s13550-025-01337-0
Primary Topic
Spondyloarthritis Studies and Treatments
Type
article
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Na[18F]F PET/CT quantification in spondyloarthritis: comparative evaluation of SUV normalization approaches

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EJNMMI Research
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Na[18F]F PET/CT quantification in spondyloarthritis: comparative evaluation of SUV normalization approaches

Robert C. Schuit, Ronald Boellaard, Robert Hemke, Conny J. van der Laken, S. Groothuizen, W.R.P. van der Heijden, Maqsood Yaqub, Gerben J. C. Zwezerijnen
article en

Abstract

Na[<sup>18</sup>F]F uptake quantification of lesions in the axial skeleton of SpA patients can be performed cross-sectionally and longitudinally with simplified uptake measures, particularly SUV<sub>peak</sub>, normalized using LBM or SV. This offers a more reliable approach to evaluating disease activity and treatment responses compared to BW.

EJNMMI ResearchVol. 15(1)
Amsterdam Neuroscience (NL), University of Amsterdam (NL)
Openalex Percentile: Top 28%
Spondyloarthritis Studies and Treatments
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