Oral and gut microbiota of elderly individuals with cognitive impairment in a Brazilian longevity hotspot
Fecal microbiota exhibited clinical-stage-specific changes, while salivary microbiota displayed more stability, underscoring microbial adaptations to the distinct. These findings highlight microbiome changes along the AD continuum, emphasizing the potential microbiome's role in healthy aging and resilience against neurodegeneration.
Authors
- João Batista Teixeira da Rocha (ORCID: https://orcid.org/0000-0003-3829-0595)
- Eduardo Rigon Zimmer (ORCID: https://orcid.org/0000-0002-5349-0053)
- Ariele Detogni
- Amanda Muliterno Domingues Lourenço de Lima
- Berenice Maria Werle
- Marco Antônio De Bastiani (ORCID: https://orcid.org/0000-0003-3924-5278)
- Laisa Zanella
- Andreza Francisco Martins (ORCID: https://orcid.org/0000-0001-6227-1920)
- Joana Emilia Senger
- Eduardo José Gaio (ORCID: https://orcid.org/0000-0003-1611-6393)
- Wyllians Vendramini Borelli
- Lavínia Perquim
- Eduarda Letícia Klafke Ebert
- João Vitor Cardoso Barboza
- Rafaela Ramalho Guerra
- Artur Francisco Schumacher‐Schuh
- Neide Maria Bruscato
- Renan Antônio Barth
- Isadora Crasnhak de Souza
- Lilian Vivian Netson
- Emilio Hideyuki Moriguchi
- Joao Senger
- Diogo O. Souza
Institutions
- Universidade Federal do Rio Grande do Sul (BR)
- Universidade Federal de Ciências da Saúde de Porto Alegre (BR)
- Instituto Federal de Educação, Ciência e Tecnologia do Rio Grande do Sul (BR)
- Hospital de Clínicas de Porto Alegre (BR)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70855_106628
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.00