Machine Learning Quantification of Amyloid‐β deposits in three brain regions of over 250 Hispanic and Non‐Hispanic White Decedents with Alzheimer Disease

This study further validates a prior published pipeline and reveals similarities and differences in Aβ densities in a diverse cohort, including cases across three institutions, demonstrating the need for more generalizable results to aid in precision medicine approaches for AD.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70855_103507
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Machine Learning Quantification of Amyloid‐β deposits in three brain regions of over 250 Hispanic and Non‐Hispanic White Decedents with Alzheimer Disease

Brittany N. Dugger, Dan Mungas, David G. Coughlin, Laurel Beckett et al.
Alzheimer s & Dementia
Dementia and Cognitive Impairment Research
article

Machine Learning Quantification of Amyloid‐β deposits in three brain regions of over 250 Hispanic and Non‐Hispanic White Decedents with Alzheimer Disease

Brittany N. Dugger, Dan Mungas, David G. Coughlin, Laurel Beckett, Juan C. Vizcarra, David Gutman, Lorena Garcia, David Garcia, Naomi Saito, Shivam Rajendra Rai Sharma, Chen‐Nee Chuah, Charles S. DeCarli, Andrew F. Teich
article en

Abstract

This study further validates a prior published pipeline and reveals similarities and differences in Aβ densities in a diverse cohort, including cases across three institutions, demonstrating the need for more generalizable results to aid in precision medicine approaches for AD.

Alzheimer s & DementiaVol. 21(S1)
Emory University (US), University of California San Diego (US), Columbia University (US), University of California, Davis (US)
Quality Education
Openalex Percentile: Top 35%
Dementia and Cognitive Impairment Research
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Machine Learning Quantification of Amyloid‐β deposits in three brain regions of over 250 Hispanic and Non‐Hispanic White Decedents with Alzheimer Disease — Brittany N. Dugger, Dan Mungas, et al. · Alzheimer s & Dementia (2025) | TGRS Research Map | TGRS