Structural alterations related to emotion dysregulation, anxiety and self-harm in adolescents borderline personality disorder. A source-based morphometry study

Our findings suggest that gray matter alterations in regions ascribed to the default mode network, cerebellum, and frontal control regions play a crucial role in emotional regulation deficits and self-injurious behaviors in adolescent BPD. This study provides new insights into the neurobiological mechanisms of BPD in youth and offering potential biomarker and targets for treatments.