Alterations in the blood‐based biomarker testing performances following correction for renal function

Our results demonstrated that while the deviations in performance metrics due to correction may be modest, they would not be negligible, particularly in cohorts with a higher proportion of CKD participants. This highlights the importance of establishing a robust correction equation for renal function to ensure the accurate real-world application of BBMs. Furthermore, it may be recommended that when reporting BBM performance the proportion of CKD within the examined samples is also disclosed.