Systemic bone loss measured by routine CT is associated with increased pain, postural decompensation, and survival in multiple myeloma
CT-based HU measurement enables longitudinal assessment of vertebral bone quality and identifies patients at risk for pain, functional decline, and poorer overall prognosis. Furthermore, HU decline increases with disease progression and might serve as additional marker for disease burden and activity.
Authors
- Katja Christina Weisel (ORCID: https://orcid.org/0000-0001-9422-6614)
- Julian Kylies
- Markus Schomacher
- Lennart Viezens (ORCID: https://orcid.org/0000-0001-9353-667X)
- Peter Obid (ORCID: https://orcid.org/0000-0003-4923-1064)
- Malte Schroeder
- Leon Leonhardt
- Tobias M. Ballhause
- Lara Krueger
Institutions
- Universität Hamburg (DE)
- University Medical Center Hamburg-Eppendorf (DE)
Publication Details
- Journal
- European Spine Journal
- Published
- 2025-12-24
- DOI
- https://doi.org/10.1007/s00586-025-09703-1
- Primary Topic
- Multiple Myeloma Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00