Ginsenoside Rh2 inhibits mesenchymal stem cell senescence by regulating mitochondrial and lysosomal function
These findings provide a potential strategy for using Rh2 to overcome the senescence of MSCs, thereby enhancing their clinical application.
Authors
- Na Lin
- Jianjian Zhuang
- Yi Ling Huang
- Yue Li
- Xiang Wang
Institutions
- Zhejiang Chinese Medical University (CN)
- Westlake University (CN)
- Affiliated Hangzhou First People's Hospital, Westlake University, School of Medicine (CN)
- Zhejiang University (CN)
Publication Details
- Journal
- Stem Cell Research & Therapy
- Published
- 2025-12-24
- DOI
- https://doi.org/10.1186/s13287-025-04741-4
- Primary Topic
- Ginseng Biological Effects and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Zhejiang Provincial Program for the Cultivation of High-Level Innovative Health Talents
- Natural Science Foundation of Zhejiang Province