Robust associations with posterior predominant amyloid PET binding

We reliably assign patients into an Aβ+<sub>(posterior)</sub> PET binding group uncovering consistent associations that suggests occipital regions should not be neglected in the appraisal of Aβ-PET. Specifically, occipital Aβ+ PET binding may be a marker of CAA and more severe cognitive impairment.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70856_098300
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Robust associations with posterior predominant amyloid PET binding

Lea T. Grinberg, Renaud La Joie, Daniel R. Schonhaut, Salvatore Spina et al.
Alzheimer s & Dementia
Dementia and Cognitive Impairment Research
article

Robust associations with posterior predominant amyloid PET binding

Lea T. Grinberg, Renaud La Joie, Daniel R. Schonhaut, Salvatore Spina, Ganna Blazhenets, Stefania Pezzoli, Jhony Alejandro Mejía‐Perez, Brad C. Dickerson, Liana G. Apostolova, William J. Jagust, Joseph Giorgio, Maria C. Carrillo, Jennifer S. Yokoyama, Susan M. Landau, William W. Seeley, Gil D. Rabinovici
article en

Abstract

We reliably assign patients into an Aβ+<sub>(posterior)</sub> PET binding group uncovering consistent associations that suggests occipital regions should not be neglected in the appraisal of Aβ-PET. Specifically, occipital Aβ+ PET binding may be a marker of CAA and more severe cognitive impairment.

Alzheimer s & DementiaVol. 21(S2)
Alzheimer's Association (US), University of California, San Francisco (US), Massachusetts General Hospital (US), University Memory and Aging Center (US), Global Brain Health Institute (US), Indiana University School of Medicine, Indiana University – Purdue University Indianapolis (US), University of Newcastle Australia (AU), University of California, Berkeley (US)
Openalex Percentile: Top 35%
Dementia and Cognitive Impairment Research
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