Investigating the effects of complement loci CFH and ARMS2/HTRA1 on Alzheimer Disease
Single SNP association analyses did not expose any significant associations between LOAD and single SNPs at the CFH or ARMS2/HTRA1 loci. Examining the haplotype association with LOAD will allow for increased power and better understanding of the risk these two loci confer to LOAD.
Authors
- Daniel A. Dorfsman
- Kristy Miskimen
- Michael Cuccaro
- Jason E. Clouse
- Sharlene D. Herington
- Yining Liu
- Sherri D. Hochstetler
- Jeffery M. M Vance
- Reneé A. Laux
- Laura J. Caywood
- Yeunjoo E. Song (ORCID: https://orcid.org/0000-0002-7452-3731)
- Ping Wang (ORCID: https://orcid.org/0009-0005-8478-466X)
- Weihuan Wang (ORCID: https://orcid.org/0000-0002-1053-6859)
- Muneeswar Gupta Nittala (ORCID: https://orcid.org/0000-0002-3802-6594)
- William K. Scott (ORCID: https://orcid.org/0000-0001-9336-6404)
- Sarada L. Fuzzell
- Alan J. Lerner
- Dawn M. Miller
- Audrey Lynn
- Alex V. Gulyayev
- Margaret Pericak‐Vance
- Noel C. Moore
- Jonathan L Haines
- Paula K. Ogrocki
- Dwight Stambolian
- SriniVas R Sadda
Institutions
- University of Miami (US)
- University of California, Los Angeles (US)
- University Hospitals of Cleveland (US)
- Doheny Eye Institute (US)
- Dr. John T. Macdonald Foundation (US)
- University School (US)
- Case Western Reserve University (US)
- University of Pennsylvania (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70855_106578
- Primary Topic
- Retinal Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00