ARTS is associated with NfL but not with <i>p</i> ‐tau217
The present study in community-based older adults without dementia suggests that ARTS scores are not influenced by Alzheimer's pathology, which often co-occurs with arteriolosclerosis. Yet, higher ARTS scores are associated with more severe axonal injury assessed by means of higher NfL scores. Both findings are in support of ARTS as a specific marker of arteriolosclerosis and cerebral small vessel disease.
Authors
- Gulam Mahfuz Chowdhury
- Julie A. Schneider (ORCID: https://orcid.org/0000-0003-0756-5007)
- Konstantinos Arfanakis (ORCID: https://orcid.org/0000-0001-9705-597X)
- Arnold M Evia (ORCID: https://orcid.org/0000-0003-2262-890X)
- Khalid Saifullah
- David A. A. Bennett
Institutions
- Rush University Medical Center (US)
- Illinois Institute of Technology (US)
- Rush University (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_101643
- Primary Topic
- Intracerebral and Subarachnoid Hemorrhage Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00