Seminal Plasma Exosomal miRNA Profiling Reveals hsa‐miR‐7‐5p as a Key Regulator of Sperm Motility in Asthenozoospermia
hsa-miR-7-5p may regulate sperm motility through the rapidly accelerated fibrosarcoma 1 -mediated gonadotropin-releasing hormone secretion and MAPK signaling networks. Our findings highlight the potential role of exosomal microRNAs in male infertility. Future prospective studies are warranted to elucidate the molecular mechanisms underlying the regulation of sperm motility.
Authors
- Jinfeng Li (ORCID: https://orcid.org/0000-0002-4312-5917)
- Wenjing Yuan (ORCID: https://orcid.org/0009-0006-3556-4879)
- En‐Zhong Li
- Xi‐Qiao Yao
- Ruo‐Qing Li
- Meng‐Li Cui
- Zhi‐Jian Zhu
- Jia‐Ning Zhang
- Shuo Zhang
Institutions
- Zhumadian Central Hospital (CN)
- Huanghuai University (CN)
Publication Details
- Journal
- Andrology
- Published
- 2025-12-24
- DOI
- https://doi.org/10.1111/andr.70159
- Primary Topic
- Sperm and Testicular Function
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Education Department of Henan Province