Mapping of immunome, brain imaging, and cognition in an aging cohort at risk for Alzheimer's disease

This study highlights the role of aging-related immunosenescence in shaping neuroimmune interactions linked to Alzheimer's disease risk. These findings underscore age-driven immune dysregulation as a key contributor to disease susceptibility and suggest potential targets for immune-based therapies to mitigate progression.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70855_102122
Primary Topic
Neuroinflammation and Neurodegeneration Mechanisms
Type
article
Field-Weighted Citation Impact
0.00
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article

Mapping of immunome, brain imaging, and cognition in an aging cohort at risk for Alzheimer's disease

Wassim Elyaman
Alzheimer s & Dementia
Neuroinflammation and Neurodegeneration Mechanisms
article

Mapping of immunome, brain imaging, and cognition in an aging cohort at risk for Alzheimer's disease

Wassim Elyaman
article en

Abstract

This study highlights the role of aging-related immunosenescence in shaping neuroimmune interactions linked to Alzheimer's disease risk. These findings underscore age-driven immune dysregulation as a key contributor to disease susceptibility and suggest potential targets for immune-based therapies to mitigate progression.

Alzheimer s & DementiaVol. 21(S1)
Columbia University (US)
Openalex Percentile: Top 39%
Neuroinflammation and Neurodegeneration Mechanisms
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Mapping of immunome, brain imaging, and cognition in an aging cohort at risk for Alzheimer's disease — Wassim Elyaman · Alzheimer s & Dementia (2025) | TGRS Research Map | TGRS