Intranasally administered muse cells attenuate neurodegeneration in Parkinson’s disease
These findings suggest that Muse cells achieve homing through the S1P-S1PR2 mechanism and intranasal administration of muse cells was efficient in reaching to the brain, which may offer a novel therapeutic strategy for Parkinson's disease.
Authors
- Zhihui Wang (ORCID: https://orcid.org/0009-0006-0546-4746)
- Haomeng Wu (ORCID: https://orcid.org/0009-0005-3872-5028)
- Xiaodong Mu (ORCID: https://orcid.org/0000-0002-5345-0780)
- Shifeng Ren
- Yajun Zhang
- Bingjie Wang
- Liwei Shao
- Zhe Lu
Institutions
- Shandong First Medical University (CN)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2025-12-24
- DOI
- https://doi.org/10.1186/s12967-025-07401-6
- Primary Topic
- Hearing, Cochlea, Tinnitus, Genetics
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Shandong Province
- Shandong First Medical University