Social Isolation and Loneliness Elevating Osteoporosis and Fracture Morbidity, Mediated by Frailty and Systemic Inflammation
Social isolation and loneliness contribute to OP and fracture incidence, partially mediated by frailty and systemic inflammation. Our findings implicated the importance of strengthening social connection and target intervention of against frailty in OP and fracture prevention.
Authors
- Shuo Zheng
- Yingxi Wei
- Xing Wang (ORCID: https://orcid.org/0000-0002-8537-7186)
- Xiaowen Ma
- Qi Wang
- Shujie Zhao
- Haolong Zhou
Institutions
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Biopsychosocial Science and Medicine
- Published
- 2025-12-22
- DOI
- https://doi.org/10.1097/psy.0000000000001461
- Primary Topic
- Bone health and osteoporosis research
- Type
- article
- Field-Weighted Citation Impact
- 0.00