Distinct patterns of oligodendroglial dysfunction in neurodegenerative diseases

This study highlights the distinct cell-intrinsic impact of mis-folded protein pathology on oligodendroglia and identifies unique signatures of oligodendroglial dysfunction that are likely to adversely affect neuronal and axonal function.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70855_104113
Primary Topic
Neurogenesis and neuroplasticity mechanisms
Type
article
Field-Weighted Citation Impact
0.00
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article

Distinct patterns of oligodendroglial dysfunction in neurodegenerative diseases

Gábor G. Kovács, Madison A. Kane, Shelley L. Forrest, Samantha Knott
Alzheimer s & Dementia
Neurogenesis and neuroplasticity mechanisms
article

Distinct patterns of oligodendroglial dysfunction in neurodegenerative diseases

Gábor G. Kovács, Madison A. Kane, Shelley L. Forrest, Samantha Knott
article en

Abstract

This study highlights the distinct cell-intrinsic impact of mis-folded protein pathology on oligodendroglia and identifies unique signatures of oligodendroglial dysfunction that are likely to adversely affect neuronal and axonal function.

Alzheimer s & DementiaVol. 21(S1)
University of Toronto (CA), Occupational Cancer Research Centre (CA), Macquarie University (AU)
Openalex Percentile: Top 29%
Neurogenesis and neuroplasticity mechanisms
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