Deep Neural Network Modeling of Circular RNA‐Mediated Epitranscriptomic Modifications in Alzheimer's Disease Progression: A Multi‐Omic Approach Using Single‐Nucleus RNA Sequencing and Spatial Epigenomics
This study identifies the essential roles of circRNAs in Alzheimer's disease progression using a robust multi-omic deep learning framework. By integrating snRNA-seq and spatial epigenomics, the findings contribute to a deeper understanding of potential therapeutic targets for Alzheimer's disease.
Authors
- Rifaldy Fajar
- Sahnaz Putri
- Prihantini Prihantini
Institutions
- Yogyakarta State University (ID)
- Bandung Institute of Technology (ID)
- Universitas Internasional Semen Indonesia (ID)
- Indonesia International Institute for Life Sciences (ID)
- Universitas Teknologi Yogyakarta (ID)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70855_102535
- Primary Topic
- Circular RNAs in diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00