Untargeted Metabolomics Reveals Novel Biomarkers and Pathways for Early Detection and Pathogenesis of Alzheimer's Disease
This study identifies distinct metabolic signatures and plasma biomarkers with diagnostic and therapeutic potential for AD. Leucine and ascorbic acid emerge as promising markers linked to cognitive decline and neuroinflammation, respectively, paving the way for early detection and targeted interventions.
Authors
- Prabhakar Tiwari (ORCID: https://orcid.org/0000-0001-6418-8928)
Institutions
- All India Institute of Medical Sciences (IN)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_097300
- Primary Topic
- Metabolomics and Mass Spectrometry Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00