Gray Matter Volume Abnormalities and the Association with the Trajectory of Symptoms and Functioning in Individuals at Clinical High Risk of Psychosis

Our findings suggest that CHR individuals show baseline differences in brain structure compared to HC, which may also predict changes in positive symptoms over the subsequent 2 years.

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Publication Details

Journal
Schizophrenia Bulletin
Published
2025-12-03
DOI
https://doi.org/10.1093/schbul/sbaf231
Primary Topic
Schizophrenia research and treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Gray Matter Volume Abnormalities and the Association with the Trajectory of Symptoms and Functioning in Individuals at Clinical High Risk of Psychosis

L. de Haan, Anthony R. James, Bart P. F. Rutten, Stephan Ruhrmann et al.
Schizophrenia Bulletin
Schizophrenia research and treatment
article

Gray Matter Volume Abnormalities and the Association with the Trajectory of Symptoms and Functioning in Individuals at Clinical High Risk of Psychosis

L. de Haan, Anthony R. James, Bart P. F. Rutten, Stephan Ruhrmann, G. Sachs, Cheryl R. Z. See, Shuqing Si, Barnaby Nelson, Lucia Valmaggia, C. Pantelis, Birte Yding Glenthoj, Neus Barrantes‐Vidal, MARK VAN DER GAAG, Gareth J. Barker, Emily Hedges, Philip McGuire, Marie-Odile Krebs, Gemma Modinos, EU-GEI High Risk Study, Matthew J Kempton, Stefania Tognin, Rodrigo Bressan, Anita Riecher-Rössler, Jim van Os
article en

Abstract

Our findings suggest that CHR individuals show baseline differences in brain structure compared to HC, which may also predict changes in positive symptoms over the subsequent 2 years.

Schizophrenia Bulletin
Délégation Paris 5 (FR), Universitat Autònoma de Barcelona (ES), Centre National de la Recherche Scientifique (FR), Inserm (FR), King's College London (GB), University of Basel (CH), Université Paris Cité (FR), Maastricht University Medical Centre (NL), Glostrup Hospital (DK), Warneford Hospital (GB), Maastricht University (NL), University of Oxford (GB), Parnassia Groep (NL), Orygen Youth Health (AU), Departament de Salut (ES), Centre Hospitalier Sainte-Anne (FR), Arkin (NL), University Hospital Cologne (DE), Melbourne Health (AU), Medical Research Network (US), Medical University of Vienna (AT), Vrije Universiteit Amsterdam (NL), Universidade Federal de São Paulo (BR), University of Amsterdam (NL)
Openalex Percentile: Top 35%
Schizophrenia research and treatment
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