Surgically induced brain‐draining lymphatic dysfunction accelerates the development of cognitive impairment
These findings suggest that impaired brain-draining lymphatics contribute to the development of cognitive impairment in both WT and TG APP/PS1 mice. Future studies should address the underlying mechanisms responsible for this observation.
Authors
- Alanna G. Spiteri (ORCID: https://orcid.org/0000-0001-6787-6195)
- Liang Jin (ORCID: https://orcid.org/0000-0001-6464-6263)
- Colin L. Masters (ORCID: https://orcid.org/0000-0003-3072-7940)
- Xin Huang (ORCID: https://orcid.org/0000-0002-7278-3070)
- Jiaqi Sun (ORCID: https://orcid.org/0000-0002-6708-1883)
- Yijun Pan
Institutions
- The University of Melbourne (AU)
- Florey Institute of Neuroscience and Mental Health (AU)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_096732
- Primary Topic
- Cerebrospinal fluid and hydrocephalus
- Type
- article
- Field-Weighted Citation Impact
- 0.00