Tracking pyrethroid resistance in arbovirus mosquito vectors: mutations I1532T and F1534C in Aedes albopictus across Europe
The present study offers the first map of the occurrence of the major Ae. albopictus kdr alleles across Europe and highlights a differential distribution of the two alleles most strongly associated with pyrethroid resistance, 1016G and 1534C. Our findings also point to the need for enhancing resistance monitoring in the Eastern Mediterranean region, where the two mutations are shown to exist in geographically close areas, with the risk of emergence of highly resistant double mutants.
Authors
- A. García Tello
- Igor Pajović (ORCID: https://orcid.org/0000-0001-8574-2094)
- Carlos Barceló (ORCID: https://orcid.org/0000-0002-8345-3229)
- Perez-Tris Javier
- Concepción Ornosa
- Katja Adam (ORCID: https://orcid.org/0000-0001-8969-7382)
- Ana L. García‐Pérez (ORCID: https://orcid.org/0000-0001-7404-1380)
- Vera Valadas (ORCID: https://orcid.org/0000-0002-7317-3901)
- Daniel Bravo‐Barriga (ORCID: https://orcid.org/0000-0003-3481-7310)
- Ognyan Mikov (ORCID: https://orcid.org/0000-0002-6003-0434)
- Alessandra della Torre (ORCID: https://orcid.org/0000-0001-7054-0027)
- Sarah Delacour‐Estrella (ORCID: https://orcid.org/0000-0001-7046-2997)
- Gilles Besnard
- Dušan Petrić (ORCID: https://orcid.org/0000-0002-8454-4341)
- Jérémy Bouyer (ORCID: https://orcid.org/0000-0002-1913-416X)
- Cintia Horváth (ORCID: https://orcid.org/0000-0002-9582-6635)
- Marlen Ines Vasquez (ORCID: https://orcid.org/0000-0002-9849-5616)
- Elena Fălcuță (ORCID: https://orcid.org/0000-0003-3433-030X)
- Gregory L’ambert
- Beniamino Caputo
- Enkelejda Velo (ORCID: https://orcid.org/0000-0001-7283-2541)
- Francisco Collantes (ORCID: https://orcid.org/0000-0002-8085-6399)
- Mihaela Kavran (ORCID: https://orcid.org/0000-0001-5210-9727)
- Mustafa Muhammed Akiner
- A. MICHAELAKIS
- R. Melero-Alcíbar
- Raimundo Outerelo
- Riccardo Paolo Lia (ORCID: https://orcid.org/0000-0001-7239-1694)
- Andrei Daniel Mihalca (ORCID: https://orcid.org/0000-0001-6076-7914)
- Toni Žitko
- Maria Louise Borg
- Rubén Bueno
- Ángeles Vázquez
- Elton Rogozi (ORCID: https://orcid.org/0000-0003-1757-1822)
- Verena Pichler (ORCID: https://orcid.org/0000-0002-7553-3704)
- Martina Micocci (ORCID: https://orcid.org/0000-0002-5341-2098)
- Eduardo Marabuto
- J. D. Luna Pinto (ORCID: https://orcid.org/0000-0001-7387-4233)
- José F. Gómez
- Domenico Otranto
- Pierre-Alain Muller
- Georgios Balatsos
- Perparim Kadriaj
- Maria Teresa Rebelo
- Raquel Medialdea-Carrera
- Eleonora Flacio
- Miguel A. Miranda
- Francis Schaffner
Institutions
- University of Primorska (SI)
- Universidad Complutense de Madrid (ES)
- International Atomic Energy Agency (AT)
- University of Medicine Tirana (AL)
- Centre de Coopération Internationale en Recherche Agronomique pour le Développement (FR)
- University of Lisbon (PT)
- University of Applied Sciences and Arts of Southern Switzerland (CH)
- Swiss Tropical and Public Health Institute (CH)
- Recep Tayyip Erdoğan University (TR)
- Cyprus University of Technology (CY)
- City University of Hong Kong (HK)
- University of Novi Sad (RS)
- University of Basel (CH)
- University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca (RO)
- Universidad de Zaragoza (ES)
- Steinbach Bible College (CA)
- Institute of Public Health (AL)
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement (FR)
- Animal, Santé, Territoires, Risques et Ecosystèmes (FR)
- Saint Camillus International University of Health and Medical Sciences (IT)
- Senckenberg Natural History Collections Dresden (DE)
- Instituto de Medicina Tropical (PY)
- Cook Research (United States) (US)
- Benaki Phytopathological Institute (GR)
- Fonctionnement et Conduite des Systèmes de Culture Tropicaux et Méditerranéens (FR)
- NEIKER, Basque Institute for Agricultural Research and Development (ES)
- Office of Disease Prevention (US)
- Croatian Hydrographic Institute (HR)
- National Center of Infectious and Parasitic Diseases (BG)
- Universitat de les Illes Balears (ES)
- University of Córdoba (ES)
- University of Bari Aldo Moro (IT)
- University of Montenegro (ME)
- Universidad de Murcia (ES)
- Sapienza University of Rome (IT)
Publication Details
- Journal
- Parasites & Vectors
- Published
- 2025-12-24
- DOI
- https://doi.org/10.1186/s13071-025-07130-1
- Citations
- 2
- Primary Topic
- Mosquito-borne diseases and control
- Type
- article
- Field-Weighted Citation Impact
- 3.76
Funders
- City University of Hong Kong
- Universität Basel
- Cyprus University of Technology
- University of Cyprus
- Universidad Complutense de Madrid
- International Atomic Energy Agency
- Universidad de Murcia
- Universidade de Lisboa
- Universidad de Zaragoza
- Centre de Coopération Internationale en Recherche Agronomique pour le Développement
- Université de Montpellier
- Universidad de Córdoba
- Universitat de les Illes Balears
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
- Directorate for Biological Sciences