Associations between classical Alzheimer’s Disease biomarkers and key proteins defining potential pathophysiological mechanisms – A multi‐analyte proteomic analysis
AD-specific proteins are moderately to strongly correlated with each other on the Alamar platform. The most significantly associated proteins with ATN & I biomarkers within the platform included markers subserving inflammation, connective tissue integrity, and vascular function. Follow up studies should be longitudinal with individuals across the AD continuum.
Authors
- Hubert Leo
- Omonigho M. Bubu (ORCID: https://orcid.org/0000-0001-7438-2628)
- Joshua L. Gills (ORCID: https://orcid.org/0000-0003-3321-4120)
Institutions
- NYU Langone Health (US)
- New York University (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70862_109869
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00