Longitudinal relationships between systemic inflammatory markers, plasma <i>p</i> ‐tau181 and entorhinal tau Positron Emission Tomography (PET)

Among cognitively unimpaired participants, early IL-6 may be protective in maintaining lower plasma and PET tau levels but sustained inflammation may contribute to later elevated tau.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70861_108488
Primary Topic
Alzheimer's disease research and treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Longitudinal relationships between systemic inflammatory markers, plasma p ‐tau181 and entorhinal tau Positron Emission Tomography (PET)

Meredith N. Braskie, Koral V Wheeler, Danielle Luu, K Yaffe et al.
Alzheimer s & Dementia
Alzheimer's disease research and treatments
article

Longitudinal relationships between systemic inflammatory markers, plasma p ‐tau181 and entorhinal tau Positron Emission Tomography (PET)

Meredith N. Braskie, Koral V Wheeler, Danielle Luu, K Yaffe, Maxwell W Hand, Sid E. O'Bryant, Marylan Davison, Noelle Lee, Arthur W. Toga, Victoria R Tennant
article en

Abstract

Among cognitively unimpaired participants, early IL-6 may be protective in maintaining lower plasma and PET tau levels but sustained inflammation may contribute to later elevated tau.

Alzheimer s & DementiaVol. 21(S7)
University of Southern California (US), University of North Texas (US), University of North Texas Health Science Center (US), University of California, San Francisco (US)
Good health and well-being
Openalex Percentile: Top 34%
Alzheimer's disease research and treatments
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