The mechanism study of targeting DPP4 in regulating ferroptosis and its influence on endometrial receptivity in PCOS
Reducing DPP4 expression not only inhibited ferroptosis but also improved the PCOS phenotype of the endometrium, ultimately influencing changes in endometrial receptivity, and indicating the ferroptosis-related protein DPP4 as a promising therapeutic target.
Authors
- Yajun He
- Fang Wang (ORCID: https://orcid.org/0000-0002-5971-2622)
- K. Wang
- J D Zhang
- Qiliang Jian
- Jiao Cai (ORCID: https://orcid.org/0009-0003-4215-5748)
- Ruifang Wang
- Chengbin Tao
- Xiuli Tian
- Nan Ding
Institutions
- Shanxi Medical University (CN)
- Lanzhou University Second Hospital (CN)
- First Affiliated Hospital of Henan University of Science and Technology (CN)
- Shanxi Provincial People’s Hospital (CN)
- Lanzhou University (CN)
Publication Details
- Journal
- Biology of Sex Differences
- Published
- 2025-12-23
- DOI
- https://doi.org/10.1186/s13293-025-00786-5
- Citations
- 1
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 1.52