The PFAS VascCog Longitudinal Study: Pilot Data

Results suggest feasibility of the new PFAS VascCog Longitudinal Study, quantifying PFAS concentrations in stored serum, calculating a composite measure of total PFAS burden, consistent with population statistics, supporting public health generalizability. Pilot data support our hypothesis that higher PFAS exposure increases dementia risk. Future findings can provide novel mechanistic insight into the impact of PFAS on cognitive health, identify new avenues for disease modification, and support PFAS regulatory efforts.