Fasting vs Nonfasting, Dose-adjusted Levothyroxine Ingestion in Hypothyroidism: A Randomized Clinical Trial
LT4 ingestion with breakfast with a 15% dose increase maintained TSH stability and improved patient well-being. Given the strong patient preference, this patient-centered approach may offer a viable alternative to fasting administration.
Authors
- Floris Helmich
- Marco Medici (ORCID: https://orcid.org/0000-0002-7271-7858)
- Roderick F. A. Tummers-de Lind van Wijngaarden
- Robin Patrick Peeters (ORCID: https://orcid.org/0000-0001-7732-9371)
- Jeresa I A Willems (ORCID: https://orcid.org/0000-0001-8478-3177)
- Daan J L van Twist
- Thijs Sluiter
Institutions
- Erasmus MC (NL)
- Zuyderland Medisch Centrum (NL)
- Erasmus University Rotterdam (NL)
Publication Details
- Journal
- The Journal of Clinical Endocrinology & Metabolism
- Published
- 2025-12-22
- DOI
- https://doi.org/10.1210/clinem/dgaf686
- Primary Topic
- Thyroid Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00