Impact of Atherosclerosis Comorbidity on Cortical Microstructure in Alzheimer's Disease Using Diffusion MRI: Evidence from an Autopsy‐Confirmed Cohort
These findings highlight the potential of cortical diffusivity in detecting distinct patterns of microstructural changes in individuals with the same ADNC severity but varying levels of ACW severity. This underscores the utility of cortical diffusivity for patient stratification in clinical practice and trials.
Authors
- Pegah Khosropanah (ORCID: https://orcid.org/0000-0002-5255-7631)
- Steven A. Chance (ORCID: https://orcid.org/0000-0001-6060-3805)
- Ian Hardingham
- Gerard R Ridgway
- Mario Torso
Institutions
- Oxford Medical Diagnostics (United Kingdom) (GB)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70862_109733
- Primary Topic
- Advanced Neuroimaging Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00