Neuroticism, omega‐3 fatty acids, and risk of incident dementia
Neuroticism is associated with lower levels of omega-3 fatty acids, particularly DHA, which may increase dementia risk, primarily through cerebrovascular mechanisms. Further research with temporally sequenced measures of neuroticism, metabolites, and dementia is needed to strengthen evidence for this pathway.
Authors
- Cornelia M. van Duijn (ORCID: https://orcid.org/0000-0002-2374-9204)
- Thomas J. Littlejohns (ORCID: https://orcid.org/0000-0003-1177-6923)
- Yaqing Gao
- Najaf Amin
Institutions
- University of Oxford (GB)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70860_104686
- Primary Topic
- Fatty Acid Research and Health
- Type
- article
- Field-Weighted Citation Impact
- 0.00