Insulin Resistance and Cognitive Function in Nondiabetic Patients With Cerebral Small Vessel Disease: Role of Brain Glymphatic Function

Both the HOMA-IR and the DTI-ALPS index are independent risk factors for cognitive function. Furthermore, the DTI-ALPS index significantly and partially mediates the relationship between the HOMA-IR and cognitive function.

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Publication Details

Journal
Brain and Behavior
Published
2025-12-01
DOI
https://doi.org/10.1002/brb3.71143
Primary Topic
Cerebrospinal fluid and hydrocephalus
Type
article
Field-Weighted Citation Impact
0.00

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article

Insulin Resistance and Cognitive Function in Nondiabetic Patients With Cerebral Small Vessel Disease: Role of Brain Glymphatic Function

Tian‐Yao Wang, Yongfeng Luo, Dan‐Hong Wu, W LU et al.
Brain and Behavior
Cerebrospinal fluid and hydrocephalus
article

Insulin Resistance and Cognitive Function in Nondiabetic Patients With Cerebral Small Vessel Disease: Role of Brain Glymphatic Function

Tian‐Yao Wang, Yongfeng Luo, Dan‐Hong Wu, W LU, Hu‐Lie Zeng, Meng‐Xiang Wang, Xiao‐Li Yang
article en

Abstract

Both the HOMA-IR and the DTI-ALPS index are independent risk factors for cognitive function. Furthermore, the DTI-ALPS index significantly and partially mediates the relationship between the HOMA-IR and cognitive function.

Brain and BehaviorVol. 15(12)
Fudan University (CN), Renji Hospital (CN), Ministry of Education (KR), Obstetrics and Gynecology Hospital of Fudan University (CN), East China Normal University (CN)
Shanghai Municipal Health Commission
Openalex Percentile: Top 38%
Cerebrospinal fluid and hydrocephalus
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